Colorectal cancer is rising in adults under 50, making it a growing concern among younger populations. This trend highlights the urgent need for timely screenings. Ongoing research is helping doctors learn more about the causes and improve early detection to save lives.

New Research Studies CRC Development

Researchers recently made an important discovery that could help us better understand how colorectal cancer (CRC) develops. In a study published in Nature Communications, scientists used mouse models to explore how certain proteins affect tumor growth.

The Spanish National Cancer Research Center team focused on a well-known protein called p53 and another protein called URI. P53 helps prevent tumors. Studies link URI to several types of cancer.

Researchers found that “if URI was eliminated or p53 levels were increased in polyps, the polyps did not develop into tumors.” They also learned that under the same conditions, “the mice with colorectal cancer lived longer.”

Now, the team’s ongoing work is focusing on the development of URI inhibitors.

“These inhibitors may have an impact on the treatment of colorectal cancer and other URI-related cancers, offering an innovative therapeutic approach to slow down tumor progression and improve patient care,” said Nabil Djouder in Medical XPress. Djouder is the head of the Growth Factors, Nutrients and Cancer Group.

Trending: Early-Onset Colorectal Cancer

As research on colorectal cancer continues, learn about your risk factors, symptoms and screening guidelines to protect your health.

Most colorectal cancers start as small growths, called polyps, on the lining of the colon (large intestine). These polyps can slowly turn into cancer over time.

Experts refer to CRC in younger people as early-onset colorectal cancer. Reports indicate CRC incidence is rising in people ages 20 to 45.

Doctors are not sure why more young people are developing CRC. It may be because of a mix of genetic and environmental factors. You may be at high risk if you have any of the following:

• Inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis
• A family history of colorectal cancer or colon polyps
• A diet low in fruits and vegetables and high in processed foods
• A history of smoking or heavy alcohol use
• Diabetes or obesity

Many early-onset CRC cases are found late because symptoms are often missed or confused with other common health issues. Some warning signs to watch for include the following:

• Changes in bowel habits
• Blood in your stool
• Unexplained weight loss or constant tiredness
• Ongoing stomach discomfort or cramping

In many cases, CRC doesn’t cause any symptoms, which is why screening is important. If you’re experiencing symptoms, talk to your doctor about screening, regardless of your age.

Timely Screenings Save Lives. Don’t Wait for Symptoms.

Colorectal cancer is a leading cause of cancer death in the United States. For adults under 50, CRC is now the No. 1 cause of cancer death in men and the second leading cause in women.

More than any diet or exercise regimen, timely screening is the best way to protect yourself from colorectal cancer.

The U.S. Preventive Services Task Force recommends that adults at average risk for CRC start regular screenings at age 45. If you have one or more risk factors, you may need to screen sooner. Your doctor can help you choose the screening that’s right for you.

Colonoscopy is the only test that not only finds signs of cancer but also removes precancerous polyps during the procedure. This helps prevent cancer from developing.

The good news is most insurance plans cover a screening colonoscopy for adults 45 and older. Contact your insurance provider to confirm your coverage.

If you choose a different screening method and get an abnormal result, a follow-up colonoscopy will be needed to check for cancer or other health concerns.

Schedule Your Colonoscopy Today at Our ASC

CRC is both preventable and highly treatable when detected early. A colonoscopy is the most efficient way to catch problems early or prevent cancer altogether.

Our Ambulatory Surgery Center (ASC) makes it easy to get the care you need:

• Timely, efficient outpatient care
• Lower costs than hospital-based procedures
• Shorter wait times and personalized attention
• A safe, comfortable environment focused on your well-being

Early detection saves lives. If you’re due for a colonoscopy or need a follow-up, don’t wait. Protect your health and schedule your screening today.